Advances in Controlled Drug Delivery. Science, Technology, by Steven M. Dinh and Puchun Liu (Eds.)

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By Steven M. Dinh and Puchun Liu (Eds.)

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Freedman, J. E . , Fabian, A . , Scribner, A . , Alpert, C. , Keaney, J. , Jr. & Loscalzo, J. Circulation 1997, 95,2115-21. 15. Oberhoff, M . , Hanke, H . , Haase, Κ. K. & Karsch, K . R. Cardiovasc Res 1998, 38,751-62. 16. Clowes, A . W . & Karnovsky, M. J. J Surg Res 1978, 24,161-8. 17. Edelman, E . , Adams, D . H. & Karnovsky, M. J. Proc Natl Acad Sci U S A 1990, 87,3773-7. 18. Karnovsky, M . J. & Edelman, E . R. ; Academic Press: 1994. 19. Ross, R. N Engl J Med 1999, 340,115-26. 20. Ross, R.

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Yoo, J. & Edelman, E. R. J Biol Chem 2001, 12,12. ; ACS Symposium Series; American Chemical Society: Washington, DC, 2003. ch003 1 2 Frederick G. P. Welt , T. Cooper Woods , and Elazer R. , 765 Old Saw Mill River Road, Tarrytown, NY 10591 Cardiovascular Division, Brigham and Women's Hospital, Boston, MA 02115 2 3 Background: Heparin is the archetypical modulator of vascular repair following arterial injury in animal models. In these models, heparin delivered either as a continuous intravenous infusion or via frequent subcutaneous dosing, inhibits neointimal hyperplasia after either balloon injury or stent implantation.

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